Cardiovascular Physiology

Staff

Current Research Projects

  • Translational Physiology with a focus on aging, life-style related diseases, and refractory diseases such as pulmonary hypertension and inflammatory bowel disease. The goal is to contribute to developing innovative new preventive and therapeutic strategies based on profound understanding of underlying pathophysiology.
  • Special interests are in the field of physiology and pathophysiology of proteinase-activated receptors, smooth muscle contraction, endothelial function, angiogenesis, metabolism and mitochondrial functions.

 

Representative Publications

  • Li X, Hiraishi K, Kumamoto K, Nakakita S, Yamashita T, Kamitori K, Ohmichi K, Ishikawa R, Kurahara L-H:
    D-Allose suppresses colitis associated carcinogenesis by reversing ER stress in macrophages and inhibiting cancer cell proliferation.
    Front. Immunol. 17: 1737504,2026
    https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2026.1737504/full?=
  • Li G, Zhao Z, Machitani M, Ishikawa R, Ishikawa K, Yokota N, Haba R, Nakamura K, Sun Z, Kurahara L-H, Hirano K:
    Elucidation of mechanisms underlying the therapeutic effects of cordycepin on pulmonary hypertension, with a focus on cell senescence and gut microbiota.
    Biomed Pharmacother 194: 118923, 2026
    https://www.sciencedirect.com/science/article/pii/S0753332225011175
  • ZhaoZ,Li G,Ohmichi K, Li X, ZhaoF, Ishikawa K, Ishikawa R, Nakamura K, Yokota N, Sun Z, Kurahara L-H:
    Lacticaseibacillus rhamnosus Probio-M9 alters the gut microbiota and mitigates pulmonary hypertension in a rat model.
    Nutrients 17(18): 2927, 2025
    https://www.mdpi.com/2072-6643/17/18/2927

Contact Information

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